Wile E. Coyote uses some inventions to try and do the ALS Ice Bucket Challenge on the Road Runner in order to catch him, but the water keeps backfiring on him. Every time the water hits him, Wile E. would say this exact phrase: "YUCK! Coyote's don't like water!"
This is the second CGI short where Wile E. speaks. The first was Wile E.'s Dream.
The ALS Ice Bucket Challenge is a real world challenge to support ALS.
Olaf the snowman from the movie Frozen made a cameo at the end of the short and hugs Wile E.
An episode of Coyote (TV series) later aired with the same name.